[FRESHERS] Dr. Reddy Hiring Research Scientist in R&D
Company: Dr. Reddy’s Institute of Life Sciences (DRILS)
Job Position: Research Scientist – Formulation R&D
Location: University of Hyderabad Campus, Gachibowli, Hyderabad
Qualifications:
- Educational Background:
- Fresh PhD or PhD + Postdoctoral Experience in Chemistry, Biochemistry, Pharmaceutical Sciences, Engineering, or Life Sciences.
- Evidence of exceptional ability in the relevant field.
- Technical Skills and Knowledge:
- Deep understanding of formulation principles and techniques.
- Knowledge of chemical and physical properties of materials used in pharmaceutical formulations.
- Proficiency in various formulation techniques and analytical methodologies.
- Interdisciplinary Abilities:
- Ability to read and understand diverse literature across many disciplines relevant to drugs/nucleic acid delivery.
- Ability to distill new ideas and apply them to work.
- Problem-Solving and Communication:
- Ability to identify challenges and bottlenecks in development and suggest mitigation proposals.
- Excellent verbal and written communication skills.
- Ability to present scientific findings clearly and concisely.
- Team and Collaborative Skills:
- A collaborative mindset.
- Ability to work effectively within a team environment.
- Analytical and Experimental Abilities:
- Strong analytical and problem-solving abilities.
- Demonstrated track record of independently interpreting experimental data and troubleshooting technical challenges.
- Workload Management:
- Willingness to handle substantial and often repetitive formulation and characterization workloads.
- Desire to rapidly learn, troubleshoot, and master new experimental techniques.
Areas of Relevant Experience:
- Drug Delivery Systems: Lipid (Liposomes, LNPs, solid-lipid nanoparticles) or polymer-based systems.
- Polymer Chemistry: Molecular weight, degradation behavior, synthesis.
- Peptide and Proteins: Basic understanding, handling, stability, drug loading in DDS.
- Controlled Drug Delivery Systems: Sustained and controlled systems (Implants, depot, in situ depot).
- Microfluidics: Preferably for lipid or polymeric nanoparticle synthesis, encapsulation, and characterization.
- Formulation/Nanoparticle Downstream Purification Methods: Techniques such as ultrafiltration and TFF.
- Formulation/Nanoparticle Characterization: Particle size and zeta potential measurements, pKa determination, viscosity.
- Microscopy Techniques: TEM, SEM, Confocal.
- Spectroscopy, Spectrometry, and Thermal Techniques: UV, Fluorescence, FTIR, Circular Dichroism, Raman, PXRD, DLS, DSC, MS, NMR.
- Size Exclusion Chromatography and Techniques for Characterizing Biopharmaceuticals:
- Analytical Techniques to Characterize Polymeric DDS: Particle size, drug content by UPLC/HPLC, drug loading, drug release.
- Analysis and Characterization of Higher Order Structures or Conformations:
- Biophysical Characterization: Size, aggregates, mechanisms of instability, thermal denaturation, ligand binding.
- Nucleic Acid Quantification Techniques: RiboGreen-style assays and NanoDrop-style spectrophotometry.
- In Vitro Cell Evaluation of DDS: Cell/cell lines handling, culture, DDS evaluation on various cell models.
- In Vivo Evaluation of DDS: Animal handling, dosing, disease model development, and evaluation of DDS.
Application Process:
Interested candidates may send their curriculum vitae by e-mail to hr@drils.org on or before 10th June 2024 with “Formulation Lab” as the subject line of the email.
Interview Process:
- Phone interview for shortlisted candidates.
- Personal interview at Dr. Reddy’s Institute of Life Sciences (optional Skype/teleconference interview if unable to attend in person).
Meta Description: Dr. Reddy’s Institute of Life Sciences is hiring a Research Scientist in Formulation R&D. Apply by June 10, 2024.